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IVF babies at greater heart risk

ANI | Updated: Nov 23, 2017 02:04 IST

Washington D.C. [USA], Nov 23 (ANI): A recent study has linked in vitro fertilization with an increased risk of congenital heart defects.

The analysis of published studies found a 45% increased risk of congenital heart defects in newborns when women become pregnant via in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) than through spontaneous conception.

The analysis included 8 studies with 25,856 children obtained from IVF techniques and 287,995 children spontaneously conceived and a total of 2289 congenital heart defects.

Congenital heart defects were found in 1.30% and 0.68% in the IVF/ICSI and spontaneous conception groups, respectively.

"We believe that IVF/ICSI pregnancies present an increased risk of CHDs as a consequence of early placental dysfunction; however this hypothesis should be demonstrated in future studies. We recommend fetal echocardiography in all pregnancies from IVF/ICSI," said lead author Paolo Cavoretto, of the IRCCS San Raffaele Hospital, in Milan, Italy.

The study appears in the journal Ultrasound in Obstetrics and Gynecology. (ANI)