Potential new vaccine target for bacterial meningitis identified

   May 25, 5:51 pm

Washington, May 25 (ANI): Researchers have identified a protein responsible for bacterial meningitis.

Bacterial meningitis is an infection of the meninges, the protective membrane that covers the spinal cord and brain.

Children, elderly patients and immunocompromised patients are at a higher risk for the development of severe bacterial meningitis.

Recently, a team of researchers at the University of Adelaide in Australia sought to identify new vaccine targets in Streptococcus pneumoniae, which is the most common cause of bacterial meningitis in the world.

Led by Dr. Abiodun Ogunniyi, the research team developed a new method of screening for bacterial genes that are expressed during meningitis in brain tissue.

Using a mouse model system, the researchers examined mice infected with two different strains of S. pneumoniae.

They identified a protein known as glycerophosphate oxidase, and showed that this protein was critical for the progression of bacteria from blood to brain in mice.

They went on to show that a vaccine against glycerophosphate oxidase protected mice from invasive pneumococcal disease.

Their results not only suggest a new strategy for immunizing against Streptococcus pneumoniae, but also provide a blueprint for discovering additional genes from other pathogens that contribute to meningitis. (ANI)

Rats' ability to link cause and effect helps understand human reasoning Mar 30, 5:55 pm
Washington, Mar 30 (ANI): A new study has indicated that even rats can imagine and they have the ability to link cause and effect such that they can expect, or imagine, something happening even if it isn't.
Full Story
Now, see up to 50m in darkness with these night vision eye-drops Mar 30, 3:49 pm
London, March 30 (ANI): Scared of the dark? Fear not as scientists have now created night vision eye drops, which enables one to see up to 50m in the dark.
Full Story
Young male monkeys prefer hanging around with dads to prepare for itinerant lifestyle Mar 29, 1:32 pm
London, Mar.29 (ANI): A new study has revealed that young male monkeys prefer to hang around with their dads, may be in order to prepare for the itinerant lifestyle they are forced to live later in life.
Full Story
Neanderthal had different ear bones than modern humans: Study Mar 29, 1:23 pm
Washington, Mar.29 (ANI): A new study has revealed that Neanderthal ear bones were different from the modern humans.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY