Chemicals in marijuana could help treat multiple sclerosis

   Oct 8, 4:03 pm

Washington, Oct 08 (ANI): Researchers have found that some chemical compounds found in marijuana can help treat multiple sclerosis-like diseases in mice by preventing inflammation in the brain and spinal cord.

Multiple sclerosis (MS) is an inflammatory disease in which the immune system attacks the nervous system. The result can be a wide range of debilitating motor, physical, and mental problems.

Dr. Ewa Kozela of Tel Aviv University said that their study looks at how compounds isolated from marijuana can be used to regulate inflammation to protect the nervous system and its functions.

Besides THC or tetrahydrocannabinol, the most plentiful and potent cannabinoid in marijuana is cannabidiol , or CBD.

The TAU researchers are particularly interested in CBD, because it offers medicinal benefits without the controversial mind-altering effects of THC.

In a 2011 study, they showed that CBD helps treat MS-like symptoms in mice by preventing immune cells in their bodies from transforming and attacking the insulating covers of nerve cells in the spinal cord.

In the latest study, the researchers set out to see if the known anti-inflammatory properties of CBD and THC could also be applied to the treatment of inflammation associated with MS.

The researchers took immune cells isolated from paralyzed mice that specifically target and harm the brain and spinal cord, and treated them with either CBD or THC. In both cases, the immune cells produced fewer inflammatory molecules, particularly one called interleukin 17, or IL-17, which is strongly associated with MS and very harmful to nerve cells and their insulating covers.

The researchers concluded that the presence of CBD or THC restrains the immune cells from triggering the production of inflammatory molecules and limits the molecules' ability to reach and damage the brain and spinal cord.

The study is published in the Journal of Neuroimmune Pharmacology. (ANI)

Gene therapy offers hope to cystic fibrosis sufferers post successful trials Jul 3, 11:39 am
London, Jul 3 (ANI): For the first time, gene therapy has offered hope to cystic fibrosis sufferers after its successful trials.
Full Story
Dengue`s tail`s tale: How virus evolves to spread more efficiently Jul 3, 11:22 am
Washington DC, Jul 3 (ANI): A team of scientists has identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defenses and spread more efficiently.
Full Story
Here`s how our brains may reconstruct past events Jul 3, 10:52 am
Washington DC, Jul 3 (ANI): A new research has revealed how the human brain might reconstruct past events.
Full Story
Implantable 'artificial pancreas' can free diabetics from daily insulin jabs Jul 2, 5:21 pm
Washington DC, Jul 2 (ANI): As per a new study, implantable "artificial pancreas" can help diabetes patients control their blood sugar.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY